A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes
نویسندگان
چکیده
منابع مشابه
Association between Glutathione S-Transferase T1, M1, and P1 Genotypes and the Risk of Colorectal Cancer
Glutathione S-transferases (GSTs) are enzymes which play an important role in the neutralization of toxic compounds and eradication of electrophilic carcinogens. Genetic polymorphisms within the genes encoding for GSTs may therefore cause variations in their enzyme activity, which may in turn influence the interindividual susceptibility to cancers. In this study, we aimed to investigate the ass...
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Mizaj (Temperament) is one of the basic concepts of Iranian Traditional Medicine (ITM), which has great importance in diagnosis and treatment of diseases, as well as maintaining the ideal healthy state of an individual. However, very little is known about the biological mechanisms of mizaj dependence treatment in practical ITM. This study was aimed to evaluate any association between the mizaj ...
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Objective(s):To the best of our knowledge, this is the first report on the contributions of GST genetic variants to the risk of diabetic retinopathy in an Iranian population. Therefore, the objective of this study was to determine whether sequence variation in glutathione S-transferase gene (GSTM1 and GSTT1) is associated with development of diabetic retinopathy in type 2 diabetes mellitus (T2D...
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PURPOSE The glutathione-S-transferase (GST)P1, GSTM1, and GSTT1 genotypes have been associated with an increased risk of prostate, bladder, and lung cancers. The aim of this study was to investigate the association between the GSTP1, GSTM1, and GSTT1 genotypes and the risk of prostate cancer in Korean men. MATERIALS AND METHODS The study group consisted of 166 patients with histologically con...
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1 Genetic Research Group, Molecular and Bioinformatics Unit, Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor DE, Malaysia. 2 Department of Genetics, Faculty of Medicine, Tonekabon Islamic Azad University, Tonekabon, Mazandaran, Iran. 3 Department of Pathology, Faculty of Medicine and Health Sciences, University Pu...
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2008
ISSN: 1756-0357
DOI: 10.1038/npre.2008.2559.1